Phosphonoformic acid trisodium salt hexa( foscarnet sodium hexahydrate | Sodium phosphonatoformate hexahydrate )

Catalog No. M28595 CAS No. 34156-56-4

Phosphonoformic acid trisodium salt hexa is an antiviral drug for the treatment of CMV retinitis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Phosphonoformic acid trisodium salt hexa
Note

Research use only, not for human use.
Brief Description

Phosphonoformic acid trisodium salt hexa is an antiviral drug for the treatment of CMV retinitis.
Description

Phosphonoformic acid trisodium salt hexa is an antiviral drug for the treatment of CMV retinitis.
In Vitro

Foscarnet sodium (Phosphonoformic acid) inhibit the human cytomegalovirus DNA polymerase (UL54) by mimicking the pyrophosphate leaving group of the nucleotide transfer reaction.Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM), HSV-1, several strains (IC50=0.4-3.5 μM).
In Vivo

——
Synonyms

foscarnet sodium hexahydrate | Sodium phosphonatoformate hexahydrate
Pathway

Others
Target

Other Targets
Recptor

α1-adrenoceptor
Research Area

——
Indication

——

Chemical Information

CAS Number

34156-56-4
Formula Weight

126.01
Molecular Formula

CH3O5P
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(P(O)(O)=O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5.

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